The Article: Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial. Nijssen, Estelle C et al. The Lancet, Volume 389, Issue 10076 The Idea:
Contrast-induced nephropathy (CIN) has historically been considered the 3rd most common cause of acute kidney injury (AKI) in patients admitted to
The Article: Aycock, Ryan D., et al. “Acute Kidney Injury After Computed Tomography: A Meta-analysis.” Annals of Emergency Medicine (2017). The Idea: Computed tomography (CT) is an important imaging modality used in the diagnosis of a variety of disorders. Imaging quality and diagnostic accuracy are improved with use of IV contrast material. There has long been a concern for potential renal injury with use of IV contrast. The goal of this study was to compare the risk of acut
The concept of Contrast-Induced Nephropathy (CIN) has long been accepted as a real, clinically relevant entity. However, this is now being questioned after a recent article was published in the Annals of Emergency Medicine… You should really read this study, but in summary, it is a single center, retrospective analysis over 5 years comparing patients who got CT scans with and without contrast, looking to see if acute kidney injury (AKI) could be attributable to contrast use.